• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia

Trendingnow

1

As Big Tech showers employees with perks to win the talent war, Nvidia built a nearly $5 trillion company by making people pay for their own lunch

2

Mark Zuckerberg feeds his cows macadamia nuts and beer to create the 'highest-quality beef in the world' on his $300 million estate in Hawaii

3

Current price of oil as of July 2, 2026

1

As Big Tech showers employees with perks to win the talent war, Nvidia built a nearly $5 trillion company by making people pay for their own lunch

2

Mark Zuckerberg feeds his cows macadamia nuts and beer to create the 'highest-quality beef in the world' on his $300 million estate in Hawaii

3

Current price of oil as of July 2, 2026
CommentaryPfizer

Commentary: Why Is Pfizer Giving Up on Parkinson’s and Alzheimer’s?

By
Allan Hugh Cole Jr.
Allan Hugh Cole Jr.
and
Bethany Cianciolo
Bethany Cianciolo
Down Arrow Button Icon
By
Allan Hugh Cole Jr.
Allan Hugh Cole Jr.
and
Bethany Cianciolo
Bethany Cianciolo
Down Arrow Button Icon
January 16, 2018, 2:16 PM ET
USA - Science - Pfizer Cancer Research
Scientist Joan Cao works in a lab at Pfizer on Friday, August 21, 2009 in San Diego, CA Many pharmaceutical companies are in a race to find cancer killing drugs. (Photo by Sandy Huffaker/Corbis via Getty Images)Sandy Huffaker—Corbis via Getty Images
Add Fortune on Google for similar content.

The pharmaceutical company Pfizer (PFE), perhaps best known for its erectile dysfunction drug Viagra, recently announced that it will shut down its research and development efforts related to neurological disorders, particularly Alzheimer’s and Parkinson’s.

The company says that this decision will result in the loss of approximately 300 research jobs, but it also suggests that savings will be applied to other Pfizer pursuits. Perhaps this will include research and development of drugs for other diseases, albeit with fewer researchers, but to date, neither the amount the company will save nor its specific use of these freed-up resources has been detailed.

As a 49 year old living with Parkinson’s disease, I think Pfizer’s decision is a disappointment. Like more than 10 million others worldwide, I depend on treatment advances to maximize my quality of life, and historically, large pharmaceutical companies have played a key role in spurring these advances. Any one of us can get these life-changing diseases. At the very least, Pfizer should think about the human element in its decisions.

On one hand, Pfizer’s decision makes some sense. Finding better treatments, not to mention cures, for brain diseases has proved difficult, particularly for Pfizer. Neurological research requires large investments of time and money, talent, patience, and resolve, before any potential success, and thus profit, can be found. In other words, this kind of research comes with a lot of risk, and Pfizer, it seems, perhaps because of its track record, has become more risk-averse when it comes to neurological diseases.

On the other hand, the potential for profit is extraordinary if and when new treatment breakthroughs occur. With respect to Parkinson’s disease, many researchers and neurologists routinely recognize that we are quite close to having several potentially “game-changing” treatments available, meaning within the next five years. Consider the 10 million people living with Parkinson’s disease and the more than 44 million people living with Alzheimer’s disease, and factor in that the frequency of both is expected to increase considerably as people live longer. Some predict a threefold increase in Alzheimer’s cases alone. Moreover, consider that, in 2017, Alzheimer’s cost the United States more than $259 billion, and that estimates suggest the cost will rise to more than $1 trillion by 2050.

I don’t know how much is spent annually on treating erectile dysfunction, but clearly, finding treatments and cures for neurological disorders has a profound positive impact on the larger economic and public good.

All is not lost. Many pharmaceutical companies continue to work on treatments for neurological diseases, as do many smaller biotech firms and academic medical research centers, and funding sources for these pursuits include private foundations as well as governments. The role that big pharma plays in research, while valuable, is often tenuous, because profit models for many diseases are not always apparent, at least in the short term.

 

That’s one reason I support the Michael J. Fox Foundation for Parkinson’s Research. Its mission is to help minimize the research and development risk that gave Pfizer cold feet. In other words, they make it less risky for companies to invest in research and development by underwriting the costs. The breakthroughs will come. We are close. Maximizing support for the efforts of those such as Michael J. Fox Foundation for Parkinson’s Research and academic medical research centers is key, especially now because other major pharmaceutical companies could follow Pfizer’s decision.

Questions about Pfizer’s decision remain, a principal one being whether curbing costs related to developing new neurological drugs will result in the price of other Pfizer drugs decreasing. I hope so, particularly in light of pharmaceutical companies frequently pointing to the high costs of developing new drugs as being the primary reason prices are so high for existing drugs.

Allan Hugh Cole Jr. is a professor and senior associate dean in the Steve Hicks School of Social Work at The University of Texas at Austin.

About the Authors
By Allan Hugh Cole Jr.
See full bioRight Arrow Button Icon
By Bethany Cianciolo
See full bioRight Arrow Button Icon
Add Fortune on Google for similar content.

Latest in Commentary

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Commentary

2
Commentary250 Years of Innovation
America’s secret weapon isn’t just innovation — It’s the freedom to fail
By Keith KrachJuly 3, 2026
32 minutes ago
rn
CommentaryCryptocurrency
Former Iran director at NSC: Crypto legislation is a ticket to sanctions evasion
By Richard NephewJuly 2, 2026
21 hours ago
m
Commentary250 Years of Innovation
McKinsey chairs: Building a more resilient industrial base may require $2 trillion in investment
By Eric Kutcher and Shubham SinghalJuly 2, 2026
21 hours ago
em
Commentary250 Years of Innovation
America’s 250th birthday has Elon Musk and a record IPO. Its 15th had Alexander Hamilton — and a stock market bubble
By Owen LamontJuly 2, 2026
1 day ago
paramount
CommentaryAntitrust
How Paramount’s theater commitments could boost local economies across the nation
By Ike BrannonJuly 2, 2026
1 day ago
elon
CommentaryChina
China has 400 private space companies. The West is barely paying attention
By Rainer ZitelmannJuly 2, 2026
1 day ago

Most Popular

As Big Tech showers employees with perks to win the talent war, Nvidia built a nearly $5 trillion company by making people pay for their own lunch
Big Tech
As Big Tech showers employees with perks to win the talent war, Nvidia built a nearly $5 trillion company by making people pay for their own lunch
By Marco Quiroz-GutierrezJuly 1, 2026
2 days ago
Mark Zuckerberg feeds his cows macadamia nuts and beer to create the 'highest-quality beef in the world' on his $300 million estate in Hawaii
Success
Mark Zuckerberg feeds his cows macadamia nuts and beer to create the 'highest-quality beef in the world' on his $300 million estate in Hawaii
By Sasha RogelbergJuly 2, 2026
18 hours ago
Current price of oil as of July 2, 2026
Personal Finance
Current price of oil as of July 2, 2026
By Joseph HostetlerJuly 2, 2026
21 hours ago
Americans are escaping the U.S. for New Zealand where house prices have hit a new low—but only wealthy Americans with $3 million spare can invest
Success
Americans are escaping the U.S. for New Zealand where house prices have hit a new low—but only wealthy Americans with $3 million spare can invest
By Emma BurleighJuly 2, 2026
20 hours ago
Today, Emily Blunt is worth $80 million thanks to her Hollywood career—but she actually wanted to be a UN Spanish translator on $80K
Success
Today, Emily Blunt is worth $80 million thanks to her Hollywood career—but she actually wanted to be a UN Spanish translator on $80K
By Orianna Rosa RoyleJuly 2, 2026
1 day ago
Egg companies made $1.22 billion in profit off a $6 carton — now they’re buying their way out of a price-fixing case with 53 million donated eggs
Law
Egg companies made $1.22 billion in profit off a $6 carton — now they’re buying their way out of a price-fixing case with 53 million donated eggs
By Wyatte Grantham-Philips and The Associated PressJuly 2, 2026
17 hours ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.