Despite the nation’s relatively smooth and speedy rollout, there’s still a lot of work to do—and a fair amount of doubt, per the week’s reports on herd immunity, that it’ll get done. As of May 5, 148.6 million Americans, or 44.7% of the total population, had received at least one dose of a COVID vaccine, up from 142.7 million a week ago, according to data from the Centers for Disease Control and Prevention. That relatively small change is dwarfed by the increase in the number of fully vaccinated individuals in the past week: 107.3 million Americans, which includes 70.1% of seniors, 41.3% of adults, and 32.3% of the total population have been fully vaccinated, up from 98 million last week.

In total, the country has administered about 250 million coronavirus vaccine doses of the 321.5 million distributed across the U.S. The vast majority of those administered vaccine doses have been the mRNA products developed by Pfizer and Moderna; the nation has administered roughly 8.5 million of Johnson & Johnson’s single-dose vaccines.

The picture across the country is increasingly disparate. New Hampshire has reached the largest share of its residents with a COVID shot at 61.2%. California, the nation’s most populous state, has vaccinated just over half of its residents; Hawaii, New Jersey, New Mexico, Pennsylvania, and much of New England has also reached more than 50% of their populations. On the other end, Mississippi has reached just 31.6% of its residents, up from 30.7% a week ago. Alabama, Idaho, Louisiana, Tennessee, and Wyoming also have reached less than 35% of their residents with COVID shots.

There’s a dire need for vaccines globally, and in a noteworthy development, the U.S. government announced it supports the lifting of patent protections on COVID vaccines to increase supply and access around the world.

Share of the population that has received at least once shot