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Lux Capital’s Deena Shakir almost died after childbirth. It reinforced why she invests in women’s health

By
Emma Hinchliffe
Emma Hinchliffe
and
Nina Ajemian
Nina Ajemian
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By
Emma Hinchliffe
Emma Hinchliffe
and
Nina Ajemian
Nina Ajemian
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August 15, 2024, 8:49 AM ET
Deena Shakir, general partner at Lux Capital.
Deena Shakir, general partner at Lux Capital. Courtesy of Lux Capital
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Good morning, Broadsheet readers! Columbia’s president resigns, Instagram failed to take down hateful comments against female U.S. politicians, and a VC’s near-death experience reinforced her passion for women’s health.

– Life or death. Deena Shakir was eight days postpartum with her third child last September when she got a bad headache. It didn’t feel normal. “It felt like a helmet was squeezing my brain,” she remembers.

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Just over a week after a C-section, Shakir still didn’t think her headache was an emergency. “Everything feels weird” after a C-section anyway, she thought. But as an investor at the venture capital firm Lux Capital who specializes in women’s health, Shakir vaguely recalled hearing that if you have a headache when you’re postpartum, you should take your blood pressure. She dug up a blood pressure cuff she’d bought for her parents in the height of COVID. “My blood pressure was literally off the chart,” she recalls.

She kept taking her blood pressure over and over, certain something must be wrong with the device; she’d never had high blood pressure readings before, including during her first two pregnancies. She made a telehealth appointment for 10 minutes later via Maven, the unicorn women’s health startup in which she’d been an early investor. At the same time, she texted Neel Shah, the company’s chief medical officer. “He said, ‘This is a true emergency,'” she remembers.

Shakir’s husband had been outside assembling a stroller for their first walk with their new baby. Instead, they got in the car and drove to the labor and delivery ward Shakir had just left, rather than risk wasting time in triage at a new emergency room. There, healthcare providers diagnosed her with postpartum preeclampsia, a life-threatening condition in which blood pressure rises to dangerous levels following birth, usually within 48 hours but sometimes as much as six weeks later. They hooked her up to an IV, where she received blood pressure medication and a magnesium drip. She learned the headache was caused by fluid in her brain and shortness of breath by fluid in her chest.

Deena Shakir, general partner at Lux Capital.
Courtesy of Lux Capital

Shakir stayed in the hospital for five days; it took three days for her blood pressure to stabilize. If she’d arrived 30 minutes later, a nurse told her, she’d likely have had a fatal stroke.

She almost couldn’t believe that after spending years becoming an expert in women’s health, she’d come so close to dying after childbirth. Without a chief medical officer from a $1.35 billion startup on speed dial, she didn’t know what would have happened. “I live in a bastion of privilege and I have access to information and really good care,” she says. “And I was still close to death so many times throughout this process.”

For Shakir, the experience reinforced why she invests in women’s health companies like the biotech company Gameto and the AI-driven fertility startup Alife; another major investment of hers is Summer Health, a pediatric telehealth startup. “A lot of my investments are trying to democratize everyone to have access to healthcare in your pocket,” she says. “In this case, it’s literally the difference between life and death.”

Postpartum preeclampsia is not well understood; doctors don’t know its cause. It was last in the headlines when Olympic runner Tori Bowie died from complications after childbirth, possibly related to preeclampsia or eclampsia. “It’s why we need to keep talking about it, it’s why we need to put more money into it,” Shakir says. “We need to figure out why these things are happening and make these solutions more accessible.”

Emma Hinchliffe
emma.hinchliffe@fortune.com

The Broadsheet is Fortune’s newsletter for and about the world’s most powerful women. Today’s edition was curated by Nina Ajemian. Subscribe here.

ALSO IN THE HEADLINES

- New school year. Columbia University president Minouche Shafik resigned from her post yesterday, months after protests over Israel and Palestine roiled the New York City campus. Her resignation is effective immediately, before students return for the fall semester, and she will take a new job with the British government overseeing its approach to international development. New York Times

- Building the foundation. Vice President Kamala Harris is building an economic policy framework to establish her priorities going into the election, as she has yet to release a policy platform. Focuses will include “making housing more affordable, lowering costs for families, taking on corporate excess and boosting small businesses,” per the Wall Street Journal.

- Take it down. Instagram failed to take down hateful comments against female U.S. politicians, according to the Center for Countering Digital Hate. Instagram left up 93% of the “toxic” comments flagged by the center, even though they went against platform policy. Cindy Southworth, head of women’s safety at Meta, said, “We will review the CCDH report and take action on any content that violates our policies.” Reuters

- Hard reset. Linda Yaccarino, chief executive officer of X, is calling for a “complete reset” for the ad industry, as X continues its antitrust lawsuit against the World Federation of Advertisers and a few of its members. She said that X “will absolutely lean in to lead and mobilize the industry.” Axios

MOVERS AND SHAKERS

Victoria’s Secret has a new CEO—Hillary Super, who was chief executive officer of Rihanna's Savage X Fenty. Previously, she was global chief executive officer of Anthropologie Group.

Fracture, a glass photo printing company, appointed Meredith English as chief executive officer. Previously, she was senior director, strategic programs & initiatives at Crocs.

InvoiceCloud, a digital bill payment service company, appointed Jessi Marcoff as chief people officer. Previously, she was chief people officer at BentoBox.

Quickbase, a work management platform, appointed Lisa Campbell to its board of directors. Most recently, she was chief marketing officer at OneTrust.

ON MY RADAR

How Amy Sherald painted herself into history Harper’s Bazaar

Providing care after Roe, these doctors met a hurdle they didn’t expect The Persistent

Gwen Walz, the coolheaded, ultracompetent political spouse New York Times

PARTING WORDS

“I believe things can change, and I believe a lot has changed since 2016.”

— Chelsea Clinton, on staying optimistic about the 2024 election

This is the web version of MPW Daily, a daily newsletter for and about the world’s most powerful women. Sign up to get it delivered free to your inbox.
About the Authors
Emma Hinchliffe
By Emma HinchliffeMost Powerful Women Editor
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Emma Hinchliffe is Fortune’s Most Powerful Women editor, overseeing editorial for the longstanding franchise. As a senior writer at Fortune, Emma has covered women in business and gender-lens news across business, politics, and culture. She is the lead author of the Most Powerful Women Daily newsletter (formerly the Broadsheet), Fortune’s daily missive for and about the women leading the business world.

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By Nina AjemianNewsletter Curation Fellow

Nina Ajemian is the newsletter curation fellow at Fortune and works on the Term Sheet and MPW Daily newsletters.

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