• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
HealthMark Cuban

Mark Cuban’s Cost Plus Drugs will begin manufacturing its own medications this week

By
Lindsey Leake
Lindsey Leake
Down Arrow Button Icon
By
Lindsey Leake
Lindsey Leake
Down Arrow Button Icon
March 4, 2024, 7:07 PM ET
Updated January 7, 2025, 4:50 PM ET
The Mark Cuban Cost Plus Drug Company will begin manufacturing its own medications in Dallas this week, cofounder and CEO Dr. Alex Oshmyansky announced Monday, March 4, 2024.
The Mark Cuban Cost Plus Drug Company will begin manufacturing its own medications in Dallas this week, cofounder and CEO Dr. Alex Oshmyansky announced Monday, March 4, 2024.Stacy Revere—Getty Images

The Mark Cuban Cost Plus Drug Company will begin manufacturing its own medications in Texas this week, cofounder and CEO Dr. Alex Oshmyansky announced Monday during a White House roundtable on lowering health care costs.

Recommended Video

“Cost Plus Drugs is proudly bringing pharmaceutical manufacturing back to the U.S., with advanced robotic and AI computer vision technology,” Oshmyansky said. “That allows us to pivot from making one drug type to another very rapidly—in principle, within four hours. 

“That way, whatever product is in shortage, we can start making that product.”

The company, which Oshmyansky launched in January 2022 alongside billionaire entrepreneur Mark Cuban, will first manufacture commercial batches of epinephrine, which is used in EpiPens, and norepinephrine, which is used to increase and maintain blood pressure, for hospital patients in intensive care. Oshmyansky didn’t mention specific dates, only that production of these two drugs would begin “this week,” followed “shortly after” by pediatric oncology drugs.

“No parent should be told the chemotherapy their child needs is not available,” Oshmyansky said. “Nobody should not get the lifesaving ICU medications they need or have to postpone their surgery because the common, cheap medications are just not available in the United States in the year 2024.”

Cost Plus Drugs’ 22,000-square-foot pharmaceutical facility in Dallas’s Deep Ellum neighborhood originally had been slated for completion in late 2022. Just as important as the drugs themselves is the way in which they’re produced, Oshmyansky said: without middlemen. 

Pills decorated with dollar bills
The Mark Cuban Cost Plus Drug Company is grounded in the simplicity of buying drugs and selling them directly to consumers at low, transparent costs, Cuban said during a White House roundtable Monday, March 4, 2024.
GP Kidd—Getty Images

White House roundtable talks pharmaceutical middlemen

The subject of intermediary pharmacy benefit managers, or PBMs, dominated discussion during the White House roundtable Monday afternoon. Cuban was also in attendance, along with public and private leaders including Democratic Kentucky Gov. Andy Beshear and Sandra Clarke, COO of Blue Shield of California.

PBMs, Cuban said, have been “shitting on independent pharmacies,” among other tactics that take advantage of the most vulnerable patients and “put stock price over health.” 

Fortune reached out to the so-called Big Three PBMs—CVS Caremark, Cigna’s Express Scripts, and UnitedHealth’s Optum Rx—for comment. Optum Rx referred Fortune to the Pharmaceutical Care Management Association (PCMA), a trade organization representing PBMs. PCMA spokesperson Greg Lopes tells Fortune in an email statement: “Mr. Cuban’s comments were unfortunate and not an accurate representation of our industry. To be clear, pharmacy benefit companies recognize the vital role pharmacies play to create access to prescription drugs for patients. In fact, PBMs support rural pharmacies through innovative programs that increase reimbursements and allow rural pharmacists to spend more time with patients. We believe a strong relationship between PBMs and all pharmacies means a better experience and more affordability for patients, which is our shared priority.”

David Joyner, president of CVS Caremark and executive vice president of CVS Health, which is a sponsor of Fortune WELL, says  in an email statement: “PBMs are built to do three things: make medicine more affordable, ensure safe use, and help drive broad access. That is exactly what payers and consumers want. Whether we are innovating to create more transparency with our TrueCost solution, putting in place utilization management that improves the use and affordability of drugs like GLP-1s, or designing tailored pharmacy networks, to drive access and value, we are laser-focused on helping as many people as possible get access to the medicines they need to stay healthy.

“Local, independently owned pharmacies serve as vital partners in our pharmacy networks. They are essential to ensuring consumers can conveniently access needed medications. On average across our national network, we reimburse independent pharmacies at a higher rate than larger regional and national chains, including CVS Pharmacy.”

Express Scripts didn’t respond by deadline.

Cost Plus Drugs is grounded in the simplicity of buying drugs and selling them directly to consumers at low, transparent costs, Cuban stressed. The online retailer now carries 2,500 medications and plans to offer as many as legally possible.

PBMs work with pharmaceutical wholesalers to set up so-called source programs, which control 90% of drug purchasing in the U.S., Oshmyansky explained, noting that Cost Plus Drugs will be as open about its manufacturing costs as it is about the prescriptions it currently sells.

“That way, we are profitable and sustainable,” Oshmyansky said, “but never extortionate.”

For more on the Mark Cuban Cost Plus Drug Co.:

  • Mark Cuban once helped his college friend save almost $10,000 on prescriptions after a ‘horrific car accident’
  • Mark Cuban’s $141K mistake: The Cost Plus Drugs cofounder says CEOs don’t understand health care coverage, and it’s costing them big
  • Mark Cuban: “There’s nobody who looks at the health care system or the pharmaceutical industry and says ‘wow, that’s well run’”
  • A doctor says a patient saved over $1,000 a month by ordering prescriptions through Mark Cuban’s online pharmacy
  • Mark Cuban has been taking on the drug industry. But which one?

Subscribe to Well Adjusted, our newsletter full of simple strategies to work smarter and live better, from the Fortune Well team. Sign up for free today.

About the Author
By Lindsey Leake
LinkedIn iconTwitter icon
See full bioRight Arrow Button Icon

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.


Latest in Health

wyle
CommentaryTV
What HBO’s ‘The Pitt’ gets right—and wrong—about treating alcohol use disorder
By Jonathan Hunt-GlassmanApril 2, 2026
5 hours ago
cancer
HealthCancer
Cancer’s grim calculus for the young: their insurance status can determine how long they survive
By Rhonda Winegar, Tara Martin, Zhaoli Liu and The ConversationApril 1, 2026
22 hours ago
Hungryroot Review 2026: What We Like About This Unique Meal Delivery
Healthmeal delivery
Hungryroot Review 2026: What We Like About This Unique Meal Delivery
By Emily PharesApril 1, 2026
22 hours ago
Nutrafol Review 2026: Ingredients, Cost, and Whether It Works
HealthDietary Supplements
Nutrafol Review 2026: Ingredients, Cost, and Whether It Works
By Christina SnyderApril 1, 2026
1 day ago
gen z
CommentaryGen Z
Gen Z is engineering an analog future — and it’s at least a $5 billion opportunity
By Luba KassovaApril 1, 2026
1 day ago
sheryl
HealthLean In
Sheryl Sandberg tapped a 25-year-old to run Lean In. Here’s her plan to close the AI gender gap
By Jacqueline MunisApril 1, 2026
2 days ago

Most Popular

Gen Z fled San Francisco for Texas and Florida. Now they’re turning ‘welcomer cities’ into the next big tech towns
Real Estate
Gen Z fled San Francisco for Texas and Florida. Now they’re turning ‘welcomer cities’ into the next big tech towns
By Fortune EditorsApril 2, 2026
11 hours ago
Current price of gold as of April 1, 2026
Personal Finance
Current price of gold as of April 1, 2026
By Fortune EditorsApril 1, 2026
1 day ago
Two-thirds of parents say their adult Gen Z kids still rely on them financially  for support—even though it's putting them under strain
Success
Two-thirds of parents say their adult Gen Z kids still rely on them financially  for support—even though it's putting them under strain
By Fortune EditorsMarch 31, 2026
2 days ago
Current price of oil as of April 1, 2026
Personal Finance
Current price of oil as of April 1, 2026
By Fortune EditorsApril 1, 2026
1 day ago
Jerome Powell says the $39 trillion national debt is ‘not unsustainable,’ but warns the trajectory ‘will not end well’
Economy
Jerome Powell says the $39 trillion national debt is ‘not unsustainable,’ but warns the trajectory ‘will not end well’
By Fortune EditorsMarch 30, 2026
3 days ago
Deutsche Bank asked AI if it’s true that AI will solve the economy’s inflation problems. The robots answered
Economy
Deutsche Bank asked AI if it’s true that AI will solve the economy’s inflation problems. The robots answered
By Fortune EditorsApril 1, 2026
23 hours ago